Apple has their own Proton, called the Game Porting Toolkit, and it works well for games that don’t need a launcher & are mainly played with a keyboard and mouse, but I’ve found that game controllers don’t work very well with it.

There’s also MoltenVK, which is Vulkan for macOS, and DXVK, a DirectX-to-Vulkan-to-Metal layer that was used to play some Windows games on macOS before the GPTK came out.